Skin UVB SKH1 mouse model treated with SFN
Part 1: RNA
Load RNA samples
Out of 30 samples, we selected 17 for this study. These are the normal tissue samples form the control, the UVA and the UVA+SFN treatment groups. normal tissue samples from the UVB_UA groups as well as tumor samples were excluded from this analysis. Additionally, one of the control samples at Week 2 (baseline) was removed after outlier analysis.
7,219 genes with zero counts in > 80% (> 13 out of 18) of samples were removed. 17,202 out of 24,421 genes were left.
[1] 7219
[1] 17202Transcripts per kilobase million (TPM) normalization
Next, we noramized the counts. To convert number of hits to the relative abundane of genes in each sample, we used transcripts per kilobase million (TPM) normalization, which is as following for the j-th sample:
1. normilize for gene length: a[i, j] = 1,000*count[i, j]/gene[i, j] length(bp)
2. normalize for seq depth (i.e. total count): a(i, j)/sum(a[, j])
3. multiply by one million
A very good comparison of normalization techniques can be found at the following video:
RPKM, FPKM and TPM, clearly explained
After the normalization, each sample’s total is 1M:
02w_CON_0 02w_SFN_0 02w_SFN_1 02w_UVB_0 02w_UVB_1 15w_CON_0 15w_CON_1 15w_SFN_0 15w_SFN_1 15w_UVB_0 15w_UVB_1 25w_CON_0
1e+06 1e+06 1e+06 1e+06 1e+06 1e+06 1e+06 1e+06 1e+06 1e+06 1e+06 1e+06
25w_CON_1 25w_SFN_0 25w_SFN_1 25w_UVB_0 25w_UVB_1
1e+06 1e+06 1e+06 1e+06 1e+06 Top 100 most abundant RNA molecules
# Separate top 100 abundant genes
tmp <- droplevels(tpm[Geneid %in% levels(tpm$Geneid)[(nrow(tpm) - 99):nrow(tpm)]])
tmp <- melt.data.table(data = tmp,
id.vars = 1:2,
measure.vars = 3:ncol(tmp),
variable.name = "Sample",
value.name = "TPM")
tmp$Week <- substr(x = tmp$Sample,
start = 1,
stop = 3)
tmp$Week <- factor(tmp$Week,
levels = unique(tmp$Week))
tmp$Treatment <- substr(x = tmp$Sample,
start = 5,
stop = 7)
tmp$Treatment <- factor(tmp$Treatment,
levels = c("CON",
"UVB",
"SFN"))
tmp$Replica <- substr(x = tmp$Sample,
start = 9,
stop = 9)
tmp$Replica <- factor(tmp$Replica,
levels = 0:1)
# Plot top 100 abundant genes
p2 <- ggplot(tmp,
aes(x = TPM,
y = Geneid,
fill = Treatment,
shape = Week)) +
# facet_wrap(~ Sex, nrow = 1) +
geom_point(size = 3,
alpha = 0.5) +
geom_vline(xintercept = 1,
linetype = "dashed")
ggplotly(p2)Bottom 100 least abundant RNA molecules
tmp <- droplevels(tpm[Geneid %in% levels(tpm$Geneid)[1:100]])
tmp <- melt.data.table(data = tmp,
id.vars = 1:2,
measure.vars = 3:ncol(tmp),
variable.name = "Sample",
value.name = "TPM")
tmp$Week <- substr(x = tmp$Sample,
start = 1,
stop = 3)
tmp$Week <- factor(tmp$Week,
levels = unique(tmp$Week))
tmp$Treatment <- substr(x = tmp$Sample,
start = 5,
stop = 7)
tmp$Treatment <- factor(tmp$Treatment,
levels = c("CON",
"UVB",
"SFN"))
tmp$Replica <- substr(x = tmp$Sample,
start = 9,
stop = 9)
tmp$Replica <- factor(tmp$Replica,
levels = 0:1)
# Plot top 100 abundant genes
p3 <- ggplot(tmp,
aes(x = TPM,
y = Geneid,
fill = Treatment,
shape = Week)) +
# facet_wrap(~ Sex, nrow = 1) +
geom_point(size = 3,
alpha = 0.5) +
geom_vline(xintercept = 1,
linetype = "dashed")
ggplotly(p3)Meta data
dmeta <- data.table(Sample = colnames(dt1)[-c(1:2)])
dmeta$time <- substr(x = dmeta$Sample,
start = 1,
stop = 3)
dmeta$time <- factor(dmeta$time,
levels = c("02w",
"15w",
"25w"))
dmeta$Week <- factor(dmeta$time,
levels = c("02w",
"15w",
"25w"),
labels = c("Week 2",
"Week 15",
"Week 25"))
dmeta$trt <- substr(x = dmeta$Sample,
start = 5,
stop = 7)
dmeta$trt <- factor(dmeta$trt,
levels = c("CON",
"UVB",
"SFN"))
dmeta$Treatment <- factor(dmeta$trt,
levels = c("CON",
"UVB",
"SFN"),
labels = c("Negative Control",
"Positive Control (UVB)",
"Sulforaphane (SFN)"))
dmeta$Replica <- substr(x = dmeta$Sample,
start = 9,
stop = 9)
dmeta$Replica <- factor(dmeta$Replica,
levels = 0:1)
datatable(dmeta,
options = list(pageLength = nrow(dmeta)))PCA of TPM
NOTE: the distributions are skewed. To make them symmetric, log transformation is often applied. However, there is an issue of zeros. In this instance, we added a small values lambda[i] equal to 1/10 of the smallest non-zero value of i-th gene.
dm.tpm <- as.matrix(tpm[, -c(1:2), with = FALSE])
rownames(dm.tpm) <- tpm$Geneid
# # Remove 02w_CON_1 sample and redo PCA
# dm.tpm <- dm.tpm[, colnames(dm.tpm) != "02w_CON_1"]
# dmeta <- dmeta[dmeta$Sample != "02w_CON_1", ]
# Add lambdas to all values, then take a log
dm.ltpm <- t(apply(X = dm.tpm,
MARGIN = 1,
FUN = function(a) {
lambda <- min(a[a > 0])/10
log(a + lambda)
}))
# PCA----
m1 <- prcomp(t(dm.ltpm),
center = TRUE,
scale. = TRUE)
s1 <- summary(m1)
s1Importance of components:
PC1 PC2 PC3 PC4 PC5 PC6 PC7 PC8 PC9 PC10 PC11 PC12
Standard deviation 66.5041 61.8206 45.2845 30.42909 28.24422 26.84136 25.01865 23.05989 22.08373 21.24391 20.87624 20.6980
Proportion of Variance 0.2571 0.2222 0.1192 0.05383 0.04637 0.04188 0.03639 0.03091 0.02835 0.02624 0.02534 0.0249
Cumulative Proportion 0.2571 0.4793 0.5985 0.65232 0.69869 0.74058 0.77696 0.80788 0.83623 0.86246 0.88780 0.9127
PC13 PC14 PC15 PC16 PC17
Standard deviation 20.28169 19.42403 19.14803 18.61200 2.085e-13
Proportion of Variance 0.02391 0.02193 0.02131 0.02014 0.000e+00
Cumulative Proportion 0.93662 0.95855 0.97986 1.00000 1.000e+00Pareto chart of variance explained by principal components
imp <- data.table(PC = colnames(s1$importance),
Variance = 100*s1$importance[2, ],
Cumulative = 100*s1$importance[3, ])
imp$PC <- factor(imp$PC,
levels = imp$PC)
p1 <- ggplot(imp,
aes(x = PC,
y = Variance)) +
geom_bar(stat = "identity",
fill = "grey",
color = "black") +
geom_line(aes(y = rescale(Cumulative,
to = c(min(Cumulative)*30/100,
30)),
group = rep(1, nrow(imp)))) +
geom_point(aes(y = rescale(Cumulative,
to = c(min(Cumulative)*30/100,
30)))) +
scale_y_continuous("% Variance Explained",
breaks = seq(0, 30, by = 5),
labels = paste(seq(0, 30, by = 5),
"%",
sep = ""),
sec.axis = sec_axis(trans = ~.,
name = "% Cumulative Variance",
breaks = seq(0, 30, length.out = 5),
labels = paste(seq(0, 100, length.out = 5),
"%",
sep = ""))) +
scale_x_discrete("") +
theme(axis.text.x = element_text(angle = 90,
hjust = 1))
# Save for publication
tiff(filename = "tmp/pca_pareto.tiff",
height = 6,
width = 8,
units = 'in',
res = 600,
compression = "lzw+p")
print(p1)
graphics.off()
print(p1)
First 3 principal components, pairwise
# Biplot while keep only the most important variables (Javier)----
# Select PC-s to pliot (PC1 & PC2)
choices <- c(1:3)
# Scores, i.e. points (df.u)
dt.scr <- data.table(m1$x[, choices])
# Add grouping variables
dt.scr$trt <- dmeta$trt
dt.scr$time <- dmeta$time
dt.scr$sample <- dmeta$Sample
# Loadings, i.e. arrows (df.v)
dt.rot <- as.data.frame(m1$rotation[, choices])
dt.rot$feat <- rownames(dt.rot)
dt.rot <- data.table(dt.rot)
# Axis labels
u.axis.labs <- paste(colnames(dt.rot)[choices],
sprintf('(%0.1f%% explained var.)',
100*m1$sdev[choices]^2/sum(m1$sdev^2)))
p1 <- ggplot(data = dt.scr,
aes(x = PC1,
y = PC2,
color = trt,
shape = time)) +
geom_point(size = 4,
alpha = 0.5) +
scale_x_continuous(u.axis.labs[1]) +
scale_y_continuous(u.axis.labs[2]) +
theme(legend.position = "none")
ggplotly(p1)
p2 <- ggplot(data = dt.scr,
aes(x = PC1,
y = PC3,
color = trt,
shape = time)) +
geom_point(size = 4,
alpha = 0.5) +
scale_x_continuous(u.axis.labs[1]) +
scale_y_continuous(u.axis.labs[3]) +
theme(legend.position = "none")
ggplotly(p2)
p3 <- ggplot(data = dt.scr,
aes(x = PC2,
y = PC3,
color = trt,
shape = time)) +
geom_point(size = 4,
alpha = 0.5) +
scale_x_continuous(u.axis.labs[2]) +
scale_y_continuous(u.axis.labs[3]) +
theme(legend.position = "none")
ggplotly(p3)
# Legend only
tmp <- ggplot(data = dt.scr,
aes(x = PC1,
y = PC2,
color = trt,
shape = time)) +
geom_point() +
scale_color_discrete("Treatment") +
scale_shape_discrete("Week")
p4 <- as_ggplot(get_legend(tmp))
# Save for publication
tiff(filename = "tmp/pca.tiff",
height = 7,
width = 9,
units = 'in',
res = 600,
compression = "lzw+p")
grid.arrange(p1, p2, p3, p4,
nrow = 2)
graphics.off()First 3 principal components, 3D
scatterplot3js(x = dt.scr$PC1,
y = dt.scr$PC2,
z = dt.scr$PC3,
color = as.numeric(dt.scr$trt),
renderer = "auto",
pch = dt.scr$sample,
size = 0.1)Differential expression analysis (DESeq2 pipeline)
Sources:
1. Analyzing RNA-seq data with DESeq2:Interactions
2. Bioconductor Question: DESeq2 time series analysis
We are testing a model with time*treatment interaction. The idea here is to find genes with significant interaction term. That would suggest that the gene expressiondifferences between the treatments depended on time. THere are several possible scenarios:
a. No difference between the negative control and the positive control groups at baseline, significant difference at the later time point. This will show the effect of the disease (UVB radiation, in this case).
b. Significant difference between the control groups at baseline, no difference at the later time point. Same as (a) above.
c. Differences between the positive control and the SFN-treated groups. Here, we are interested in the reversal of UVB effect. Again, the interaction term will need to be significant for the reasons described above.
# Relevel: make all comparisons with the positive control (UVB)
dmeta$trt <- factor(dmeta$trt,
levels = c("UVB",
"CON",
"SFN"))
dtm<- as.matrix(dt1[, dmeta$Sample,
with = FALSE])
rownames(dtm) <- dt1$Geneid
dds <- DESeqDataSetFromMatrix(countData = dtm,
colData = dmeta,
~ time + trt + time:trt)
# If all samples contain zeros, geometric means cannot be
# estimated. Change default 'type = "ratio"' to 'type = "poscounts"'.
# Type '?DESeq2::estimateSizeFactors' for more details.
dds <- estimateSizeFactors(object = dds,
type = "poscounts")
# Run DESeq----
dds <- DESeq(object = dds,
# test = "LRT",
# reduced = ~ time + trt,
fitType = "local",
sfType = "ratio",
parallel = FALSE)using pre-existing size factors
estimating dispersions
gene-wise dispersion estimates
mean-dispersion relationship
final dispersion estimates
fitting model and testing# NOTE (from DESeq help file, section Value):
# A DESeqDataSet object with results stored as metadata columns.
# These results should accessed by calling the results function.
# By default this will return the log2 fold changes and p-values
# for the last variable in the design formula.
# See results for how to access results for other variables.
# In this case, the last term is the interaction term trt:time
# NOTE:
# Likelihood ratio test (LRT) (chi-squared test) for GLM will only return
# the results for the difference between the full and the reduced model
resultsNames(dds)[1] "Intercept" "time_15w_vs_02w" "time_25w_vs_02w" "trt_CON_vs_UVB" "trt_SFN_vs_UVB" "time15w.trtCON" "time25w.trtCON"
[8] "time15w.trtSFN" "time25w.trtSFN" # Model matrix
mm1 <- model.matrix(~ time + trt + time:trt, dmeta)
mm1 (Intercept) time15w time25w trtCON trtSFN time15w:trtCON time25w:trtCON time15w:trtSFN time25w:trtSFN
1 1 0 0 1 0 0 0 0 0
2 1 0 0 0 1 0 0 0 0
3 1 0 0 0 1 0 0 0 0
4 1 0 0 0 0 0 0 0 0
5 1 0 0 0 0 0 0 0 0
6 1 1 0 1 0 1 0 0 0
7 1 1 0 1 0 1 0 0 0
8 1 1 0 0 1 0 0 1 0
9 1 1 0 0 1 0 0 1 0
10 1 1 0 0 0 0 0 0 0
11 1 1 0 0 0 0 0 0 0
12 1 0 1 1 0 0 1 0 0
13 1 0 1 1 0 0 1 0 0
14 1 0 1 0 1 0 0 0 1
15 1 0 1 0 1 0 0 0 1
16 1 0 1 0 0 0 0 0 0
17 1 0 1 0 0 0 0 0 0
attr(,"assign")
[1] 0 1 1 2 2 3 3 3 3
attr(,"contrasts")
attr(,"contrasts")$time
[1] "contr.treatment"
attr(,"contrasts")$trt
[1] "contr.treatment"Results
Effect of UVB at Week 2
res_con_uvb_week2 <- results(dds,
contrast = c(0,0,0,1,0,0,0,0,0),
alpha = 0.1)
res_con_uvb_week2 <- res_con_uvb_week2[order(res_con_uvb_week2$padj,
decreasing = FALSE),]
summary(res_con_uvb_week2)
out of 17202 with nonzero total read count
adjusted p-value < 0.1
LFC > 0 (up) : 1546, 9%
LFC < 0 (down) : 1537, 8.9%
outliers [1] : 0, 0%
low counts [2] : 2335, 14%
(mean count < 2)
[1] see 'cooksCutoff' argument of ?results
[2] see 'independentFiltering' argument of ?results# How many adjusted p-values were less than 0.05?
sum(res_con_uvb_week2$padj < 0.1,
na.rm = TRUE)[1] 3083# MA plot
# Save for publication
tiff(filename = "tmp/ma_w2_con_uvb.tiff",
height = 6,
width = 7,
units = 'in',
res = 600,
compression = "lzw+p")
plotMA(res_con_uvb_week2,
main = "Control vs. UVB at Week 2",
alpha = 0.8)
graphics.off()
plotMA(res_con_uvb_week2,
main = "Control vs. UVB at Week 2",
alpha = 0.8)
Protective effect of SFN at Week 2
res_sfn_uvb_week2 <- results(dds,
contrast = c(0,0,0,0,1,0,0,0,0),
alpha = 0.1)
res_sfn_uvb_week2 <- res_sfn_uvb_week2[order(res_sfn_uvb_week2$padj,
decreasing = FALSE),]
summary(res_sfn_uvb_week2)
out of 17202 with nonzero total read count
adjusted p-value < 0.1
LFC > 0 (up) : 26, 0.15%
LFC < 0 (down) : 35, 0.2%
outliers [1] : 0, 0%
low counts [2] : 3669, 21%
(mean count < 5)
[1] see 'cooksCutoff' argument of ?results
[2] see 'independentFiltering' argument of ?results# How many adjusted p-values were less than 0.05?
sum(res_sfn_uvb_week2$padj < 0.1,
na.rm = TRUE)[1] 61# MA plot
# Save for publication
tiff(filename = "tmp/ma_w2_sfn_uvb.tiff",
height = 6,
width = 7,
units = 'in',
res = 600,
compression = "lzw+p")
print(plotMA(res_sfn_uvb_week2,
main = "UVB+SFN vs UVB at Week 2",
alpha = 0.8))NULLgraphics.off()
print(plotMA(res_sfn_uvb_week2,
main = "UVB+SFN vs UVB at Week 2",
alpha = 0.8))NULL
Genes that were significantly differentiated at both timepoints
lgene.w2.con <- unique(res_con_uvb_week2@rownames[res_con_uvb_week2$padj < 0.1])
lgene.w2.sfn <- unique(res_sfn_uvb_week2@rownames[res_sfn_uvb_week2$padj < 0.1])
lgene.w2 <- lgene.w2.con[lgene.w2.con %in% lgene.w2.sfn]
lgene.w2 <- lgene.w2 [!is.na(lgene.w2 )]
lgene.w2 [1] "Utrn" "Stom" "Tesc" "Cited4" "Cdhr1" "Slc7a11" "Mki67" "Cyp26b1" "Smc2" "Mad2l1" "Slc4a7" "Ankrd23"
[13] "Ifitm3" "Etv3" "Pla2g4d" "Fetub" "Kif11" "Ccl6" "Has3" "Il19" "A4galt" "Otud1" "Msn" "Nqo1"
[25] "Dbf4" "Cblb" "Tbc1d24" "Elmo2" "Cd163" "Esd" "Rfx2" "Gsta1" "Slurp1" "Arntl2" "Vldlr" "Tmem173"
[37] "Gpx2" "Slfn9" "Adh7" "Sprr2i" "Bcl2l15"Plot of DESeq-normalizedcounts of genes significant in both comparisons at Week 2:
# Get the DESeq-normalize counts
dp1 <- list()
for (i in 1:length(lgene.w2)) {
out <- plotCounts(dds,
gene = lgene.w2[[i]],
intgroup = c("trt",
"time"),
returnData = TRUE)
dp1[[i]] <- data.table(Geneid = lgene.w2[[i]],
Sample = rownames(out),
out)
}
dp1 <- rbindlist(dp1)
dp1$trt <- factor(dp1$trt,
levels = c("CON",
"UVB",
"SFN"))
dp1$time <- factor(dp1$time,
levels = c("02w",
"15w",
"25w"),
labels = c("Week 2",
"Week 15",
"Week 25"))
dp1$Geneid <- factor(dp1$Geneid,
levels = lgene.w2)
dp1[, mu := mean(count,
na.rm = TRUE),
by = c("Geneid",
"trt",
"time")]
dmu <- unique(dp1[, -c("Sample",
"count")])
head(dmu)List of 1
$ axis.text.x:List of 11
..$ family : NULL
..$ face : NULL
..$ colour : NULL
..$ size : NULL
..$ hjust : num 1
..$ vjust : NULL
..$ angle : num 45
..$ lineheight : NULL
..$ margin : NULL
..$ debug : NULL
..$ inherit.blank: logi FALSE
..- attr(*, "class")= chr [1:2] "element_text" "element"
- attr(*, "class")= chr [1:2] "theme" "gg"
- attr(*, "complete")= logi FALSE
- attr(*, "validate")= logi TRUE
Did down-up-down trend persist?
dp1.tmp <- dp1[dp1$Geneid %in% unique(dmu.w2$Geneid[dmu.w2$up.dn]), ]
dmu.tmp <- dmu[dmu$Geneid %in% unique(dmu.w2$Geneid[dmu.w2$up.dn]), ]
p1 <- ggplot(dp1.tmp,
aes(x = time,
y = count,
group = trt,
fill = trt)) +
facet_wrap(~ Geneid,
scale = "free_y") +
geom_point(position = position_dodge(0.5),
shape = 21,
size = 5,
color = "black") +
geom_line(data = dmu.tmp,
aes(x = time,
y = mu,
group = trt,
colour = trt),
position = position_dodge(0.5),
alpha = 0.5,
size = 2) +
scale_x_discrete("") +
scale_y_continuous("DESeq-Normalized Counts") +
scale_fill_discrete("Treatment")
print(p1)
List of 1
$ axis.text.x:List of 11
..$ family : NULL
..$ face : NULL
..$ colour : NULL
..$ size : NULL
..$ hjust : num 1
..$ vjust : NULL
..$ angle : num 45
..$ lineheight : NULL
..$ margin : NULL
..$ debug : NULL
..$ inherit.blank: logi FALSE
..- attr(*, "class")= chr [1:2] "element_text" "element"
- attr(*, "class")= chr [1:2] "theme" "gg"
- attr(*, "complete")= logi FALSE
- attr(*, "validate")= logi TRUE
Did up-down-up trend persist?
dp1.tmp <- dp1[dp1$Geneid %in% unique(dmu.w2$Geneid[dmu.w2$dn.up]), ]
dmu.tmp <- dmu[dmu$Geneid %in% unique(dmu.w2$Geneid[dmu.w2$dn.up]), ]
p1 <- ggplot(dp1.tmp,
aes(x = time,
y = count,
group = trt,
fill = trt)) +
facet_wrap(~ Geneid,
scale = "free_y") +
geom_point(position = position_dodge(0.5),
shape = 21,
size = 5,
color = "black") +
geom_line(data = dmu.tmp,
aes(x = time,
y = mu,
group = trt,
colour = trt),
position = position_dodge(0.5),
alpha = 0.5,
size = 2) +
scale_x_discrete("") +
scale_y_continuous("DESeq-Normalized Counts") +
scale_fill_discrete("Treatment")
print(p1)
In many of these genes, UVB+SFN moved closer to UVB over time.
Heatmap for Week 2 differentially methylated genes
up.dn.w2 <- unique(as.character(dmu.w2$Geneid[dmu.w2$up.dn]))
dn.up.w2 <- unique(as.character(dmu.w2$Geneid[dmu.w2$dn.up]))
ll <- unique(c(up.dn.w2,
dn.up.w2))
# 36 genes
con_uvb_week2 <- data.table(Geneid = res_con_uvb_week2@rownames,
log2FoldChange = res_con_uvb_week2@listData$log2FoldChange)
sfn_uvb_week2 <- data.table(Geneid = res_sfn_uvb_week2@rownames,
log2FoldChange = -res_sfn_uvb_week2@listData$log2FoldChange)
t1 <- merge(con_uvb_week2[con_uvb_week2$Geneid %in% ll, ],
sfn_uvb_week2[sfn_uvb_week2$Geneid %in% ll, ],
by = "Geneid")
colnames(t1)[2:3] <- c("Control vs. UVB",
"UVB vs. SFN+UVB")
t1 <- t1[order(t1$`Control vs. UVB`,
decreasing = TRUE), ]
write.csv(t1,
file = "tmp/w2_sign_changes.csv",
row.names = FALSE)
ll <- melt.data.table(data = t1,
id.vars = 1,
measure.vars = 2:3,
variable.name = "Comparison",
value.name = "Gene Expression Diff")
ll$Comparison <- factor(ll$Comparison,
levels = c("Control vs. UVB",
"UVB vs. SFN+UVB"))
lvls <- ll[ll$Comparison == "Control vs. UVB", ]
ll$Geneid <- factor(ll$Geneid,
levels = lvls$Geneid[order(lvls$`Gene Expression Diff`)])
# Add dendrogram----
dt.dndr <- data.frame(t1[Geneid %in% levels(ll$Geneid), ])
rownames(dt.dndr) <- dt.dndr$Gene
dt.dndr <- dt.dndr[, -1]
# Compute distances between genes----
sampleDists <- dist(dt.dndr)
# Make dendrogram data----
dhc <- as.dendrogram(hclust(d = sampleDists),
horiz = TRUE)
ddata <- dendro_data(dhc,
type = "rectangle")
# Segment data----
dtp1 <- segment(ddata)
# Hitmap data----
dtp2 <- ll
dtp2$Geneid <- factor(dtp2$Geneid,
levels = ddata$labels$label)
offset.size <- 4
p1 <- ggplot(data = dtp2) +
coord_polar("y",
start = -0.3,
direction = -1) +
geom_tile(aes(x = as.numeric(Comparison),
y = Geneid,
fill = `Gene Expression Diff`),
color = "white") +
geom_text(data = dtp2[Comparison == "Control vs. UVB", ],
aes(x = rep(1.75,
nlevels(Geneid)),
y = Geneid,
angle = 90 + seq(from = 30,
to = 330,
length.out = nlevels(Geneid))[as.numeric(Geneid)] +
offset.size,
label = unique(Geneid)),
hjust = 0) +
geom_text(data = dtp2[Geneid == levels(dtp2$Geneid)[1], ],
aes(x = 1:nlevels(Comparison),
y = rep(-offset.size,
nlevels(Comparison)),
angle = 0,
label = levels(Comparison)),
hjust = 1,
size = 5) +
scale_fill_gradient2(low = "red",
high = "green",
mid = "grey",
midpoint = 0,
name = "") +
scale_y_discrete("",
expand = c(0, 0)) +
theme(plot.title = element_text(hjust = 0.5),
axis.title.x = element_blank(),
axis.text.x = element_blank(),
axis.ticks.x = element_blank(),
axis.title.y = element_blank(),
axis.text.y = element_blank(),
axis.ticks.y = element_blank(),
panel.background = element_blank(),
legend.position = "bottom",
legend.text = element_text(size = 15),
legend.direction = "horizontal",
legend.key.width = unit(1, "in"),
legend.key.height = unit(0.3, "in")) +
geom_segment(data = dtp1,
aes(x = -sqrt(y) + 0.5,
y = x,
xend = -sqrt(yend) + 0.5,
yend = xend),
size = 1)
tiff(filename = "tmp/skin_ubv_sfn_hitmap_with_phylo.tiff",
height = 8,
width = 8,
units = 'in',
res = 600,
compression = "lzw+p")
plot(p1)
graphics.off()
print(p1)
Venn Diagram, Week 2
# 1. Ctrl vs. UVB
# adjusted p-value < 0.1
# LFC > 0 (up) : 1546, 9%
# LFC < 0 (down) : 1537, 8.9%
# 23 genes down-up-down
# 2. SFN+UVB vs. UVB
# adjusted p-value < 0.1
# LFC > 0 (up) : 26, 0.15%
# LFC < 0 (down) : 35, 0.2%
# 13 gens up-down-up
p1 <- ggplot() +
geom_circle(aes(x0 = c(1, 2, 1, 2),
y0 = c(1, 1, 4, 4),
r = rep(1, 4),
color = factor(c(2, 1, 1, 2))),
size = 2) +
geom_text(aes(x = rep(c(0.5, 1.5, 2.5), 2),
y = rep(c(1, 4), each = 3),
label = format(c(26, 13, 35, 1546, 23, 1537),
big.mark = ","))) +
scale_color_manual(values = c("green", "red")) +
theme_void() +
theme(legend.position = "none")
tiff(filename = "tmp/skin_ubv_sfn_w2_venn.tiff",
height = 6,
width = 4,
units = 'in',
res = 600,
compression = "lzw+p")
plot(p1)
graphics.off()
print(p1)
Interactions terms
Tests if the effect of NOT treating with UVB vs. treating with UVB is different at Week 15 compared to Week 2:
res_int_con_uvb_week <- results(dds,
name = "time15w.trtCON",
alpha = 0.1)
res_int_con_uvb_week <- res_int_con_uvb_week[order(res_int_con_uvb_week$padj,
decreasing = FALSE),]
print(res_int_con_uvb_week)
summary(res_int_con_uvb_week)
# How many adjusted p-values were less than 0.05?
sum(res_int_con_uvb_week$padj < 0.1,
na.rm = TRUE)
# MA plot
print(plotMA(res_int_con_uvb_week,
main = "(Control vs. UVB) x TIme Interaction",
alpha = 0.9))
Tests if the effect of treating with UVB+SFN vs. treating with UVB is different at Week 15 compared to Week 2:
res_int_sfn_uvb_week <- results(dds,
name = "time15w.trtSFN",
alpha = 0.1)
res_int_sfn_uvb_week <- res_int_sfn_uvb_week[order(res_int_sfn_uvb_week$padj,
decreasing = FALSE),]
print(res_int_sfn_uvb_week)
summary(res_int_sfn_uvb_week)
# How many adjusted p-values were less than 0.05?
sum(res_int_sfn_uvb_week$padj < 0.1,
na.rm = TRUE)
# MA plot
print(plotMA(res_int_sfn_uvb_week))
# NOTE: same as
# res <- results(dds,
# alpha = 0.05)
# res <- res[order(res$padj, decreasing = FALSE),]
# resNOTE: By default, the results(dds)* prints the results for the last level of the last term, i.e. here it was for for the interaction term SFN vs. UVB at Week 15 vs. Week 2.
Genes with both interactions being significant
lgene.con <- unique(res_int_con_uvb_week@rownames[res_int_con_uvb_week$padj < 0.1])
lgene.sfn <- unique(res_int_sfn_uvb_week@rownames[res_int_sfn_uvb_week$padj < 0.1])
lgene <- lgene.con[lgene.con %in% lgene.sfn]
lgene <- lgene[!is.na(lgene)]
lgenePlot of DESeq-normalizedcounts of genes with smallest adjusted p-value for the interaction term:
# Get the DESeq-normalize counts
dp1 <- list()
for (i in 1:length(lgene)) {
out <- plotCounts(dds,
gene = lgene[[i]],
intgroup = c("trt",
"time"),
returnData = TRUE)
dp1[[i]] <- data.table(Geneid = lgene[[i]],
Sample = rownames(out),
out)
}
dp1 <- rbindlist(dp1)
dp1$trt <- factor(dp1$trt,
levels = c("CON",
"UVB",
"SFN"))
dp1$time <- factor(dp1$time,
levels = c("02w",
"15w"),
labels = c("Week 2",
"Week 15"))
dp1$Geneid <- factor(dp1$Geneid,
levels = lgene)
dp1[, mu := mean(count,
na.rm = TRUE),
by = c("Geneid",
"trt",
"time")]
dmu <- unique(dp1[, -c("Sample",
"count")])
p1 <- ggplot(dp1,
aes(x = time,
y = count,
group = trt,
fill = trt)) +
facet_wrap(~ Geneid,
scale = "free_y") +
geom_point(position = position_dodge(0.5),
shape = 21,
size = 5,
color = "black") +
geom_line(data = dmu,
aes(x = time,
y = mu,
group = trt,
colour = trt),
position = position_dodge(0.5),
alpha = 0.5,
size = 2) +
scale_x_discrete("") +
scale_y_continuous("DESeq-Normalized Counts") +
scale_fill_discrete("Treatment")
print(p1)Compare to the plot of TPM-normalizedcounts of genes with smallest adjusted p-value for the interaction term:
# Examine TPM values for the same genes
tmp <- tpm[Geneid %in% lgene, ]
tmp$Geneid <- factor(tmp$Geneid,
levels = lgene)
tmp <- melt.data.table(data = tmp,
id.vars = 1,
measure.vars = 3:ncol(tmp),
variable.name = "Sample",
value.name = "TPM")
tmp <- merge(dmeta,
tmp,
by = "Sample")
p1 <- ggplot(tmp,
aes(x = Week,
y = TPM,
fill = Treatment,
group = Treatment)) +
facet_wrap(~ Geneid,
scales = "free_y") +
geom_point(position = position_dodge(0.5),
shape = 21,
size = 5,
color = "black")+
scale_x_discrete("")
plot(p1)Session Information
sessionInfo()---
title: "Skin UVB SKH1 mouse model treated with SFN "
output:
  html_notebook:
    toc: yes
    toc_float: yes
    code_folding: hide
---

# Part 1: RNA
```{r header, echo = FALSE, message = FALSE, error = FALSE, warning  =FALSE}
# if (!requireNamespace("BiocManager", quietly = TRUE))
#     install.packages("BiocManager")
# BiocManager::install("DESeq2")

require(knitr)
require(data.table)
require(DT)
require(DESeq2)
require(readxl)
require(BiocParallel)
require(ggplot2)
require(plotly)
require(threejs)
require(scales)
require(gridExtra)
require(ggpubr)
require(ggdendro)
require(ggforce)

# NOTE: on DESeq2 Output: 'baseMean' is the average of the normalized count values, 
# divided by the size factors, taken over all samples in the DESeqDataSet
```

## Load RNA samples
Out of 30 samples, we selected 17 for this study. These are the normal tissue samples form the control, the UVA and the UVA+SFN treatment groups. normal tissue samples from the UVB_UA groups as well as tumor samples were excluded from this analysis. Additionally, one of the control samples at Week 2 (baseline) was removed after outlier analysis.    
7,219 genes with zero counts in > 80% (> 13 out of 18) of samples were removed. 17,202 out of 24,421 genes were left. 
         
```{r data_rna, warning = FALSE, echo = FALSE, message = FALSE}
# Load data----
dt0 <- fread("data/renyi_dedup_rnaseq_data/featurescounts_uvb-skin_dedup_renyi_2-9-2018.csv",
             skip = 1)

# Remove unused columns----
dt1 <- dt0[, c(1, 6:ncol(dt0)), with = FALSE]

cnames <- colnames(dt1)[-c(1:2)]
cnames <- gsub(x = cnames,
               pattern = ".dedup.bam",
               replacement = "")
colnames(dt1)[-c(1:2)] <- cnames

# ATTENTION! In this analysis, we will only examine controls and SFN
# Also, removed cancer cell samples
tnames <- substr(x = colnames(dt1), 
                 start = 3,
                 stop = 3)

gnames <- substr(x = colnames(dt1), 
                 start = 5,
                 stop = 7)

dt1 <- dt1[, gnames %in% c("id",
                           "th",
                           "CON",
                           "UVB",
                           "SFN" ) &
             tnames != "t",
           with = FALSE]
# 18 samples left

# Remove sample '02w_CON_1' as an outlier
# See 'skin_uvb_sfn_exclude_con2w1_v1' for details
dt1 <- dt1[, colnames(dt1) != "02w_CON_1", with = FALSE]

# Remove genes with zero counts in > 80% (> 13 out of 17) of samples
tmp <- dt1[, -c(1:2)] == 0
tmp <- rowSums(tmp) > 13
sum(tmp)

dt1 <- droplevels(dt1[!tmp, ])
nrow(dt1)
# 17,202 out of 24,421 genes left

datatable(head(dt1, 10),
          rownames = FALSE,
          options = list(pageLength = 10),
          caption = "Table 1: first 10 rows of the count table")
```

## Transcripts per kilobase million (TPM) normalization
Next, we noramized the counts. To convert number of hits to  the relative abundane of genes in each sample, we used ***transcripts per kilobase million (TPM)*** normalization, which is as following for the j-th sample:       
1. normilize for gene length: a[i, j] = 1,000*count[i, j]/gene[i, j] length(bp)     
2. normalize for seq depth (i.e. total count): a(i, j)/sum(a[, j])     
3. multiply by one million     
A very good comparison of normalization techniques can be found at the following video:    
[RPKM, FPKM and TPM, clearly explained](https://www.rna-seqblog.com/rpkm-fpkm-and-tpm-clearly-explained/)
     
After the normalization, each sample's total is 1M:
     
```{r tpm, warning = FALSE, echo = FALSE, message = FALSE}
# Normalize counts to TPM
tmp <- 1000*dt1[, 3:ncol(dt1)]/dt1$Length
tpm <- data.table(Geneid = dt1$Geneid,
                  Length = dt1$Length,
                  apply(tmp,
                        2,
                        function(a) {
                          10^6*(a/sum(a))
                        }))
colSums(tpm[, -c(1:2)])

formatRound(datatable(head(tpm, 10),
                      rownames = FALSE,
                      options = list(pageLength = 10),
                      caption = "Table 2: transcripts per kilobase million (TPM) normalized counts"),
            columns = 3:ncol(tpm),
            digits = 2)

# Total TPM
total <- rowSums(tpm[, 3:ncol(tpm)])

# Sort genes by relative abundancy
tpm$Geneid <- factor(tpm$Geneid ,
                     levels = tpm$Geneid[order(total,
                                               decreasing = FALSE)])
```

# Top 100 most abundant RNA molecules
```{r most_abundant}
# Separate top 100 abundant genes
tmp <- droplevels(tpm[Geneid %in% levels(tpm$Geneid)[(nrow(tpm) - 99):nrow(tpm)]])

tmp <- melt.data.table(data = tmp,
                       id.vars = 1:2,
                       measure.vars = 3:ncol(tmp),
                       variable.name = "Sample",
                       value.name = "TPM")

tmp$Week <- substr(x = tmp$Sample,
                   start = 1,
                   stop = 3)
tmp$Week <- factor(tmp$Week,
                   levels = unique(tmp$Week))


tmp$Treatment <- substr(x = tmp$Sample,
                        start = 5,
                        stop = 7)
tmp$Treatment <- factor(tmp$Treatment,
                        levels = c("CON", 
                                   "UVB",
                                   "SFN"))

tmp$Replica <- substr(x = tmp$Sample,
                      start = 9,
                      stop = 9)
tmp$Replica <- factor(tmp$Replica,
                      levels = 0:1)

# Plot top 100 abundant genes
p2 <- ggplot(tmp,
             aes(x = TPM,
                 y = Geneid,
                 fill = Treatment,
                 shape = Week)) +
  # facet_wrap(~ Sex, nrow = 1) +
  geom_point(size = 3,
             alpha = 0.5) +
  geom_vline(xintercept = 1,
             linetype = "dashed")
ggplotly(p2)
```

# Bottom 100 least abundant RNA molecules
```{r least_abundant}
tmp <- droplevels(tpm[Geneid %in% levels(tpm$Geneid)[1:100]])

tmp <- melt.data.table(data = tmp,
                       id.vars = 1:2,
                       measure.vars = 3:ncol(tmp),
                       variable.name = "Sample",
                       value.name = "TPM")

tmp$Week <- substr(x = tmp$Sample,
                   start = 1,
                   stop = 3)
tmp$Week <- factor(tmp$Week,
                   levels = unique(tmp$Week))


tmp$Treatment <- substr(x = tmp$Sample,
                        start = 5,
                        stop = 7)
tmp$Treatment <- factor(tmp$Treatment,
                        levels = c("CON", 
                                   "UVB",
                                   "SFN"))

tmp$Replica <- substr(x = tmp$Sample,
                      start = 9,
                      stop = 9)
tmp$Replica <- factor(tmp$Replica,
                      levels = 0:1)

# Plot top 100 abundant genes
p3 <- ggplot(tmp,
             aes(x = TPM,
                 y = Geneid,
                 fill = Treatment,
                 shape = Week)) +
  # facet_wrap(~ Sex, nrow = 1) +
  geom_point(size = 3,
             alpha = 0.5) +
  geom_vline(xintercept = 1,
             linetype = "dashed")
ggplotly(p3)
```

# Meta data
```{r meta}
dmeta <- data.table(Sample = colnames(dt1)[-c(1:2)])

dmeta$time <- substr(x = dmeta$Sample,
                     start = 1,
                     stop = 3)
dmeta$time <- factor(dmeta$time,
                     levels = c("02w",
                                "15w",
                                "25w"))
dmeta$Week <- factor(dmeta$time,
                     levels = c("02w",
                                "15w",
                                "25w"),
                     labels = c("Week 2",
                                "Week 15",
                                "Week 25"))

dmeta$trt <- substr(x = dmeta$Sample,
                    start = 5,
                    stop = 7)
dmeta$trt <- factor(dmeta$trt,
                    levels = c("CON", 
                               "UVB",
                               "SFN"))
dmeta$Treatment <- factor(dmeta$trt,
                          levels = c("CON", 
                                     "UVB",
                                     "SFN"),
                          labels = c("Negative Control",
                                     "Positive Control (UVB)",
                                     "Sulforaphane (SFN)"))

dmeta$Replica <- substr(x = dmeta$Sample,
                        start = 9,
                        stop = 9)
dmeta$Replica <- factor(dmeta$Replica,
                        levels = 0:1)

datatable(dmeta,
          options = list(pageLength = nrow(dmeta)))
```

# PCA of TPM
NOTE: the distributions are skewed. To make them symmetric, log transformation is often applied. However, there is an issue of zeros. In this instance, we added a small values ***lambda[i]*** equal to 1/10 of the smallest non-zero value of *i*-th gene. 
```{r pca}
dm.tpm <- as.matrix(tpm[, -c(1:2), with = FALSE])
rownames(dm.tpm) <- tpm$Geneid

# # Remove 02w_CON_1 sample and redo PCA
# dm.tpm <- dm.tpm[, colnames(dm.tpm) != "02w_CON_1"]
# dmeta <- dmeta[dmeta$Sample != "02w_CON_1", ]

# Add lambdas to all values, then take a log
dm.ltpm <- t(apply(X = dm.tpm,
                      MARGIN = 1,
                      FUN = function(a) {
                        lambda <- min(a[a > 0])/10
                        log(a + lambda)
                      }))

# PCA----
m1 <- prcomp(t(dm.ltpm),
             center = TRUE,
             scale. = TRUE)

s1 <- summary(m1)
s1
```

# Pareto chart of variance explained by principal components
```{r pca_var_plot}
imp <- data.table(PC = colnames(s1$importance),
                  Variance = 100*s1$importance[2, ],
                  Cumulative = 100*s1$importance[3, ])
imp$PC <- factor(imp$PC,
                 levels = imp$PC)
p1 <- ggplot(imp,
             aes(x = PC,
                 y = Variance)) +
  geom_bar(stat = "identity",
           fill = "grey",
           color = "black") +
  geom_line(aes(y = rescale(Cumulative,
                            to = c(min(Cumulative)*30/100,
                                   30)),
                group = rep(1, nrow(imp)))) +
  geom_point(aes(y = rescale(Cumulative,
                             to = c(min(Cumulative)*30/100,
                                    30)))) +
  scale_y_continuous("% Variance Explained",
                     breaks = seq(0, 30, by = 5),
                     labels = paste(seq(0, 30, by = 5),
                                    "%",
                                    sep = ""),
                     sec.axis = sec_axis(trans = ~.,
                                         name = "% Cumulative Variance",
                                         breaks = seq(0, 30, length.out = 5),
                                         labels = paste(seq(0, 100, length.out = 5),
                                                        "%",
                                                        sep = ""))) +
  scale_x_discrete("") +
  theme(axis.text.x = element_text(angle = 90,
                                   hjust = 1))

# Save for publication
tiff(filename = "tmp/pca_pareto.tiff",
     height = 6,
     width = 8,
     units = 'in',
     res = 600,
     compression = "lzw+p")
print(p1)
graphics.off()

print(p1)
```

# First 3 principal components, pairwise
```{r pca_plots}
# Biplot while keep only the most important variables (Javier)----
# Select PC-s to pliot (PC1 & PC2)
choices <- c(1:3)

# Scores, i.e. points (df.u)
dt.scr <- data.table(m1$x[, choices])
# Add grouping variables
dt.scr$trt <- dmeta$trt
dt.scr$time <- dmeta$time
dt.scr$sample <- dmeta$Sample

# Loadings, i.e. arrows (df.v)
dt.rot <- as.data.frame(m1$rotation[, choices])
dt.rot$feat <- rownames(dt.rot)
dt.rot <- data.table(dt.rot)

# Axis labels
u.axis.labs <- paste(colnames(dt.rot)[choices], 
                     sprintf('(%0.1f%% explained var.)', 
                             100*m1$sdev[choices]^2/sum(m1$sdev^2)))

p1 <- ggplot(data = dt.scr,
             aes(x = PC1,
                 y = PC2,
                 color = trt,
                 shape = time)) +
  geom_point(size = 4,
             alpha = 0.5) +
  scale_x_continuous(u.axis.labs[1]) +
  scale_y_continuous(u.axis.labs[2]) +
  theme(legend.position = "none")
ggplotly(p1)

p2 <- ggplot(data = dt.scr,
             aes(x = PC1,
                 y = PC3,
                 color = trt,
                 shape = time)) +
  geom_point(size = 4,
             alpha = 0.5) +
  scale_x_continuous(u.axis.labs[1]) +
  scale_y_continuous(u.axis.labs[3]) +
  theme(legend.position = "none")
ggplotly(p2)

p3 <- ggplot(data = dt.scr,
             aes(x = PC2,
                 y = PC3,
                 color = trt,
                 shape = time)) +
  geom_point(size = 4,
             alpha = 0.5) +
  scale_x_continuous(u.axis.labs[2]) +
  scale_y_continuous(u.axis.labs[3]) +
  theme(legend.position = "none")
ggplotly(p3)

# Legend only
tmp <- ggplot(data = dt.scr,
             aes(x = PC1,
                 y = PC2,
                 color = trt,
                 shape = time)) +
  geom_point() +
  scale_color_discrete("Treatment") +
  scale_shape_discrete("Week")
p4 <- as_ggplot(get_legend(tmp))

# Save for publication
tiff(filename = "tmp/pca.tiff",
     height = 7,
     width = 9,
     units = 'in',
     res = 600,
     compression = "lzw+p")
grid.arrange(p1, p2, p3, p4, 
             nrow = 2)
graphics.off()
```

# First 3 principal components, 3D
```{r pca_3d, fig.height = 10, fig.width = 10}
scatterplot3js(x = dt.scr$PC1, 
               y = dt.scr$PC2, 
               z = dt.scr$PC3, 
               color = as.numeric(dt.scr$trt),
               renderer = "auto",
               pch = dt.scr$sample,
               size = 0.1)
```

# Differential expression analysis (DESeq2 pipeline)
Sources:    
1. [Analyzing RNA-seq data with DESeq2:Interactions](https://www.bioconductor.org/packages/devel/bioc/vignettes/DESeq2/inst/doc/DESeq2.html#interactions)     
2. [Bioconductor Question: DESeq2 time series analysis](https://support.bioconductor.org/p/97430/)      
We are testing a model with time*treatment interaction. The idea here is to find genes with significant interaction term. That would suggest that the gene expressiondifferences between the treatments depended on time. THere are several possible scenarios:    
a. No difference between the negative control and the positive control groups at baseline, significant difference at the later time point. This will show the effect of the disease (UVB radiation, in this case).     
b. Significant difference between the control groups at baseline, no difference at the later time point. Same as (a) above.     
c. Differences between the positive control and the SFN-treated groups. Here, we are interested in the reversal of UVB effect. Again, the interaction term will need to be significant for the reasons described above.      

```{r deseq2}
# Relevel: make all comparisons with the positive control (UVB)
dmeta$trt <- factor(dmeta$trt,
                    levels = c("UVB",
                               "CON",
                               "SFN"))

dtm<- as.matrix(dt1[, dmeta$Sample,
                    with = FALSE])
rownames(dtm) <- dt1$Geneid

dds <- DESeqDataSetFromMatrix(countData = dtm, 
                              colData = dmeta,
                              ~ time + trt + time:trt)
# If all samples contain zeros, geometric means cannot be
# estimated. Change default 'type = "ratio"' to 'type = "poscounts"'.
# Type '?DESeq2::estimateSizeFactors' for more details.
dds <- estimateSizeFactors(object = dds,
                           type = "poscounts")

# Run DESeq----
dds <- DESeq(object = dds,
             # test = "LRT",
             # reduced = ~ time + trt,
             fitType = "local",
             sfType = "ratio",
             parallel = FALSE)

# NOTE (from DESeq help file, section Value):
# A DESeqDataSet object with results stored as metadata columns. 
# These results should accessed by calling the results function. 
# By default this will return the log2 fold changes and p-values
# for the last variable in the design formula. 
# See results for how to access results for other variables.
# In this case, the last term is the interaction term trt:time

# NOTE: 
# Likelihood ratio test (LRT) (chi-squared test) for GLM will only return 
# the results for the difference between the full and the reduced model

resultsNames(dds)

# Model matrix
mm1 <- model.matrix(~ time + trt + time:trt, dmeta)
mm1
```

# Results
## Effect of UVB at Week 2
```{r deseq2_results_week2_con_uvb}
res_con_uvb_week2 <- results(dds,
                             contrast = c(0,0,0,1,0,0,0,0,0),
                             alpha = 0.1)
res_con_uvb_week2 <- res_con_uvb_week2[order(res_con_uvb_week2$padj,
                                                   decreasing = FALSE),]
summary(res_con_uvb_week2)

# How many adjusted p-values were less than 0.05?
sum(res_con_uvb_week2$padj < 0.1, 
    na.rm = TRUE)

# MA plot
# Save for publication
tiff(filename = "tmp/ma_w2_con_uvb.tiff",
     height = 6,
     width = 7,
     units = 'in',
     res = 600,
     compression = "lzw+p")
plotMA(res_con_uvb_week2,
             main = "Control vs. UVB at Week 2",
             alpha = 0.8)
graphics.off()

plotMA(res_con_uvb_week2,
             main = "Control vs. UVB at Week 2",
             alpha = 0.8)
```

## Protective effect of SFN at Week 2
```{r deseq2_results_week2_sfn_uvb}
res_sfn_uvb_week2 <- results(dds,
                             contrast = c(0,0,0,0,1,0,0,0,0),
                             alpha = 0.1)
res_sfn_uvb_week2 <- res_sfn_uvb_week2[order(res_sfn_uvb_week2$padj,
                                                   decreasing = FALSE),]
summary(res_sfn_uvb_week2)

# How many adjusted p-values were less than 0.05?
sum(res_sfn_uvb_week2$padj < 0.1, 
    na.rm = TRUE)

# MA plot
# Save for publication
tiff(filename = "tmp/ma_w2_sfn_uvb.tiff",
     height = 6,
     width = 7,
     units = 'in',
     res = 600,
     compression = "lzw+p")
print(plotMA(res_sfn_uvb_week2,
             main = "UVB+SFN vs UVB at Week 2",
             alpha = 0.8))
graphics.off()

print(plotMA(res_sfn_uvb_week2,
             main = "UVB+SFN vs UVB at Week 2",
             alpha = 0.8))
```

## Genes that were significantly differentiated at both timepoints
```{r sign_w2}
lgene.w2.con <- unique(res_con_uvb_week2@rownames[res_con_uvb_week2$padj < 0.1])
lgene.w2.sfn <- unique(res_sfn_uvb_week2@rownames[res_sfn_uvb_week2$padj < 0.1])
lgene.w2 <- lgene.w2.con[lgene.w2.con %in% lgene.w2.sfn]
lgene.w2 <- lgene.w2 [!is.na(lgene.w2 )]
lgene.w2
```

Plot of DESeq-normalizedcounts of genes significant in both comparisons at Week 2:   

```{r deseq2_w2sign_deseqnorm}
# Get the DESeq-normalize counts
dp1 <- list()
for (i in 1:length(lgene.w2)) {
  out <- plotCounts(dds, 
                    gene = lgene.w2[[i]],
                    intgroup = c("trt",
                                 "time"),
                    returnData = TRUE)
  dp1[[i]] <- data.table(Geneid = lgene.w2[[i]],
                         Sample = rownames(out),
                         out)
}
dp1 <- rbindlist(dp1)
dp1$trt <- factor(dp1$trt,
                  levels = c("CON",
                             "UVB",
                             "SFN"))
dp1$time <- factor(dp1$time,
                   levels = c("02w",
                              "15w",
                              "25w"),
                   labels = c("Week 2",
                              "Week 15",
                              "Week 25"))
dp1$Geneid <- factor(dp1$Geneid,
                     levels = lgene.w2)
dp1[, mu := mean(count,
                 na.rm = TRUE),
    by = c("Geneid",
           "trt",
           "time")]
dmu <- unique(dp1[, -c("Sample",
                       "count")])
head(dmu)
```

```{r deseq2_w2sign_deseqnorm_w2_up_dn, echo = FALSE, message = FALSE, fig.height = 6, fig.width = 8}
dmu.w2 <- dmu[time == "Week 2", ]
dmu.w2[, up.dn := (mu[trt == "UVB"] > mu[trt == "CON"]) &
               (mu[trt == "UVB"] > mu[trt == "SFN"]),
       by = Geneid]
p1 <- ggplot(dmu.w2[up.dn == TRUE, ],
             aes(x = trt,
                 y = mu,
                 group = Geneid,
                 fill = trt)) +
        facet_wrap(~ Geneid,
                   scale = "free_y") +
        geom_line(position = position_dodge(0.5)) +
        geom_point(position = position_dodge(0.5),
                   shape = 21,
                   size = 3,
                   color = "black") +
        scale_x_discrete("") +
        scale_y_continuous("Differentially Expressed Genes at Week 2") +
        scale_fill_discrete("Treatment") +
        ggtitle("Genes Upregulated by UVB")
theme(axis.text.x = element_text(angle = 45,
                                 hjust = 1))

tiff(filename = "tmp/w2_up_dn.tiff",
     height = 6,
     width = 8,
     units = 'in',
     res = 300,
     compression = "lzw+p")
print(p1)
graphics.off()

print(p1)
```

## Did down-up-down trend persist?
```{r deseq2_w2sign_deseqnorm_plot_all_up_dn, fig.height = 10, fig.width = 12}
dp1.tmp <- dp1[dp1$Geneid %in% unique(dmu.w2$Geneid[dmu.w2$up.dn]), ]
dmu.tmp <- dmu[dmu$Geneid %in% unique(dmu.w2$Geneid[dmu.w2$up.dn]), ]
p1 <- ggplot(dp1.tmp,
             aes(x = time,
                 y = count,
                 group = trt,
                 fill = trt)) +
  facet_wrap(~ Geneid,
             scale = "free_y") +
  geom_point(position = position_dodge(0.5),
             shape = 21,
             size = 5,
             color = "black") +
  geom_line(data = dmu.tmp,
            aes(x = time,
                y = mu,
                group = trt,
                colour = trt),
            position = position_dodge(0.5),
            alpha = 0.5,
            size = 2) +
  scale_x_discrete("") +
  scale_y_continuous("DESeq-Normalized Counts") +
  scale_fill_discrete("Treatment")
print(p1)
```

```{r deseq2_w2sign_deseqnorm_w2_dn_up, echo = FALSE, message = FALSE, fig.height = 6, fig.width = 8}
dmu.w2[, dn.up := (mu[trt == "UVB"] < mu[trt == "CON"]) &
               (mu[trt == "UVB"] < mu[trt == "SFN"]),
       by = Geneid]
p2 <- ggplot(dmu.w2[dn.up == TRUE, ],
             aes(x = trt,
                 y = mu,
                 group = Geneid,
                 fill = trt)) +
        facet_wrap(~ Geneid,
                   scale = "free_y") +
        geom_line(position = position_dodge(0.5)) +
        geom_point(position = position_dodge(0.5),
                   shape = 21,
                   size = 3,
                   color = "black") +
        scale_x_discrete("") +
        scale_y_continuous("Differentially Expressed Genes at Week 2") +
        scale_fill_discrete("Treatment") +
        ggtitle("Genes Downregulated by UVB")
theme(axis.text.x = element_text(angle = 45,
                                 hjust = 1))

tiff(filename = "tmp/w2_dn_up.tiff",
     height = 6,
     width = 8,
     units = 'in',
     res = 600,
     compression = "lzw+p")
print(p2)
graphics.off()

print(p2)
```

## Did up-down-up trend persist?
```{r deseq2_w2sign_deseqnorm_plot_all_dn_up, fig.height = 10, fig.width = 12}
dp1.tmp <- dp1[dp1$Geneid %in% unique(dmu.w2$Geneid[dmu.w2$dn.up]), ]
dmu.tmp <- dmu[dmu$Geneid %in% unique(dmu.w2$Geneid[dmu.w2$dn.up]), ]
p1 <- ggplot(dp1.tmp,
             aes(x = time,
                 y = count,
                 group = trt,
                 fill = trt)) +
  facet_wrap(~ Geneid,
             scale = "free_y") +
  geom_point(position = position_dodge(0.5),
             shape = 21,
             size = 5,
             color = "black") +
  geom_line(data = dmu.tmp,
            aes(x = time,
                y = mu,
                group = trt,
                colour = trt),
            position = position_dodge(0.5),
            alpha = 0.5,
            size = 2) +
  scale_x_discrete("") +
  scale_y_continuous("DESeq-Normalized Counts") +
  scale_fill_discrete("Treatment")
print(p1)
```

In many of these genes, UVB+SFN moved closer to UVB over time.

## Heatmap for Week 2 differentially methylated genes
```{r w2_heatmap, fig.height=8, fig.width=8}
up.dn.w2 <- unique(as.character(dmu.w2$Geneid[dmu.w2$up.dn]))
dn.up.w2 <- unique(as.character(dmu.w2$Geneid[dmu.w2$dn.up]))
ll <- unique(c(up.dn.w2,
               dn.up.w2))
# 36 genes

con_uvb_week2 <- data.table(Geneid = res_con_uvb_week2@rownames,
                            log2FoldChange = res_con_uvb_week2@listData$log2FoldChange)

sfn_uvb_week2 <- data.table(Geneid = res_sfn_uvb_week2@rownames,
                            log2FoldChange = -res_sfn_uvb_week2@listData$log2FoldChange)

t1 <- merge(con_uvb_week2[con_uvb_week2$Geneid %in% ll, ],
            sfn_uvb_week2[sfn_uvb_week2$Geneid %in% ll, ],
            by = "Geneid")
colnames(t1)[2:3] <- c("Control vs. UVB",
                       "UVB vs. SFN+UVB")
t1 <- t1[order(t1$`Control vs. UVB`,
               decreasing = TRUE), ]
write.csv(t1,
          file = "tmp/w2_sign_changes.csv",
          row.names = FALSE)

ll <- melt.data.table(data = t1,
                      id.vars = 1,
                      measure.vars = 2:3,
                      variable.name = "Comparison",
                      value.name = "Gene Expression Diff")
ll$Comparison <- factor(ll$Comparison,
                        levels = c("Control vs. UVB",
                                   "UVB vs. SFN+UVB"))
lvls <- ll[ll$Comparison == "Control vs. UVB", ]
ll$Geneid <- factor(ll$Geneid,
                    levels = lvls$Geneid[order(lvls$`Gene Expression Diff`)])

# Add dendrogram----
dt.dndr <- data.frame(t1[Geneid %in% levels(ll$Geneid), ])
rownames(dt.dndr) <- dt.dndr$Gene
dt.dndr <- dt.dndr[, -1]

# Compute distances between genes----
sampleDists <- dist(dt.dndr)

# Make dendrogram data----
dhc <- as.dendrogram(hclust(d = sampleDists),
                     horiz = TRUE)
ddata <- dendro_data(dhc, 
                     type = "rectangle")

# Segment data----
dtp1 <- segment(ddata)

# Hitmap data----
dtp2 <- ll
dtp2$Geneid <- factor(dtp2$Geneid,
                      levels = ddata$labels$label)

offset.size <- 4

p1 <- ggplot(data = dtp2) +
  coord_polar("y",
              start = -0.3,
              direction = -1) +
  geom_tile(aes(x =  as.numeric(Comparison),
                y = Geneid, 
                fill = `Gene Expression Diff`),
            color = "white") +
  geom_text(data = dtp2[Comparison == "Control vs. UVB", ],
            aes(x = rep(1.75,
                        nlevels(Geneid)),
                y = Geneid,
                angle = 90 + seq(from = 30,
                                 to = 330,
                                 length.out = nlevels(Geneid))[as.numeric(Geneid)] + 
                  offset.size,
                label = unique(Geneid)),
            hjust = 0) +
  geom_text(data = dtp2[Geneid == levels(dtp2$Geneid)[1], ],
            aes(x = 1:nlevels(Comparison),
                y = rep(-offset.size,
                        nlevels(Comparison)),
                angle = 0,
                label = levels(Comparison)),
            hjust = 1,
            size = 5) +
  scale_fill_gradient2(low = "red", 
                       high = "green", 
                       mid = "grey", 
                       midpoint = 0, 
                       name = "") +
  scale_y_discrete("",
                   expand = c(0, 0)) +
  theme(plot.title = element_text(hjust = 0.5),
        axis.title.x = element_blank(),
        axis.text.x = element_blank(),
        axis.ticks.x = element_blank(),
        axis.title.y = element_blank(),
        axis.text.y = element_blank(),
        axis.ticks.y = element_blank(),
        panel.background = element_blank(),
        legend.position = "bottom",
        legend.text = element_text(size = 15),
        legend.direction = "horizontal",
        legend.key.width = unit(1, "in"),
        legend.key.height = unit(0.3, "in")) +
  geom_segment(data = dtp1,
               aes(x = -sqrt(y) + 0.5,
                   y = x, 
                   xend = -sqrt(yend) + 0.5,
                   yend = xend),
               size = 1) 

tiff(filename = "tmp/skin_ubv_w2_sfn_hitmap_with_phylo.tiff",
     height = 8,
     width = 8,
     units = 'in',
     res = 600,
     compression = "lzw+p")
plot(p1)
graphics.off()

print(p1)
```

## Venn Diagram, Week 2
```{r w2-venn, fig.height=6,fig.width=4}
# 1. Ctrl vs. UVB
# adjusted p-value < 0.1
# LFC > 0 (up)       : 1546, 9%
# LFC < 0 (down)     : 1537, 8.9%
# 23 genes down-up-down

# 2. SFN+UVB vs. UVB
# adjusted p-value < 0.1
# LFC > 0 (up)       : 26, 0.15%
# LFC < 0 (down)     : 35, 0.2%
# 13 gens up-down-up

p1 <- ggplot() +
  geom_circle(aes(x0 = c(1, 2, 1, 2),
                  y0 = c(1, 1, 4, 4),
                  r = rep(1, 4),
                  color = factor(c(2, 1, 1, 2))),
              size = 2) +
  geom_text(aes(x = rep(c(0.5, 1.5, 2.5), 2),
                y = rep(c(1, 4), each = 3),
                label = format(c(26, 13, 35, 1546, 23, 1537),
                               big.mark = ","))) +
  scale_color_manual(values = c("green", "red")) +
  theme_void() +
  theme(legend.position = "none")

tiff(filename = "tmp/skin_ubv_sfn_w2_venn.tiff",
     height = 6,
     width = 4,
     units = 'in',
     res = 600,
     compression = "lzw+p")
plot(p1)
graphics.off()

print(p1)
```


## Interactions terms
Tests if the effect of NOT treating with UVB vs. treating with UVB is different at Week 15 compared to Week 2:    
```{r deseq2_week2_week15_results_int_con_uvb}
res_int_con_uvb_week <- results(dds, 
                                name = "time15w.trtCON",
                                alpha = 0.1)
res_int_con_uvb_week <- res_int_con_uvb_week[order(res_int_con_uvb_week$padj,
                                                   decreasing = FALSE),]
print(res_int_con_uvb_week)
summary(res_int_con_uvb_week)

# How many adjusted p-values were less than 0.05?
sum(res_int_con_uvb_week$padj < 0.1, 
    na.rm = TRUE)

# MA plot
print(plotMA(res_int_con_uvb_week,
             main = "(Control vs. UVB) x TIme Interaction",
             alpha = 0.9))

```

Tests if the effect of treating with UVB+SFN vs. treating with UVB is different at Week 15 compared to Week 2:    
```{r deseq2_week2_week15_results_int_sfn_uvb}
res_int_sfn_uvb_week <- results(dds, 
                                name = "time15w.trtSFN",
                                alpha = 0.1)
res_int_sfn_uvb_week <- res_int_sfn_uvb_week[order(res_int_sfn_uvb_week$padj,
                                                   decreasing = FALSE),]
print(res_int_sfn_uvb_week)
summary(res_int_sfn_uvb_week)

# How many adjusted p-values were less than 0.05?
sum(res_int_sfn_uvb_week$padj < 0.1, 
    na.rm = TRUE)

# MA plot
print(plotMA(res_int_sfn_uvb_week))

# NOTE: same as 
# res <- results(dds, 
#                   alpha = 0.05)
# res <- res[order(res$padj, decreasing = FALSE),]
# res
```

**NOTE**: By default, the **results(dds)*** prints the results for the last level of the last term, i.e. here it was for for the interaction term SFN vs. UVB at Week 15 vs. Week 2.
       
# Genes with both interactions being significant
```{r sign_int}
lgene.con <- unique(res_int_con_uvb_week@rownames[res_int_con_uvb_week$padj < 0.1])
lgene.sfn <- unique(res_int_sfn_uvb_week@rownames[res_int_sfn_uvb_week$padj < 0.1])
lgene <- lgene.con[lgene.con %in% lgene.sfn]
lgene <- lgene[!is.na(lgene)]
lgene
```

       
Plot of DESeq-normalizedcounts of genes with smallest adjusted p-value for the interaction term:     
```{r deseq2_week2_week15_top9_deseqnorm, fig.height = 6, fig.width = 8}
# Get the DESeq-normalize counts
dp1 <- list()
for (i in 1:length(lgene)) {
  out <- plotCounts(dds, 
                    gene = lgene[[i]],
                    intgroup = c("trt",
                                 "time"),
                    returnData = TRUE)
  dp1[[i]] <- data.table(Geneid = lgene[[i]],
                         Sample = rownames(out),
                         out)
}
dp1 <- rbindlist(dp1)
dp1$trt <- factor(dp1$trt,
                  levels = c("CON",
                             "UVB",
                             "SFN"))
dp1$time <- factor(dp1$time,
                   levels = c("02w",
                              "15w"),
                   labels = c("Week 2",
                              "Week 15"))
dp1$Geneid <- factor(dp1$Geneid,
                     levels = lgene)
dp1[, mu := mean(count,
                 na.rm = TRUE),
    by = c("Geneid",
           "trt",
           "time")]
dmu <- unique(dp1[, -c("Sample",
                       "count")])

p1 <- ggplot(dp1,
             aes(x = time,
                 y = count,
                 group = trt,
                 fill = trt)) +
  facet_wrap(~ Geneid,
             scale = "free_y") +
  geom_point(position = position_dodge(0.5),
             shape = 21,
             size = 5,
             color = "black") +
  geom_line(data = dmu,
            aes(x = time,
                y = mu,
                group = trt,
                colour = trt),
            position = position_dodge(0.5),
            alpha = 0.5,
            size = 2) +
  scale_x_discrete("") +
  scale_y_continuous("DESeq-Normalized Counts") +
  scale_fill_discrete("Treatment")
print(p1)
```
      
Compare to the plot of TPM-normalizedcounts of genes with smallest adjusted p-value for the interaction term:     
```{r deseq2_week2_week15_tpmnorm, fig.height = 6, fig.width = 8}
# Examine TPM values for the same genes
tmp <- tpm[Geneid %in% lgene, ]
tmp$Geneid <- factor(tmp$Geneid,
                     levels = lgene)
tmp <- melt.data.table(data = tmp,
                       id.vars = 1,
                       measure.vars = 3:ncol(tmp),
                       variable.name = "Sample",
                       value.name = "TPM")
tmp <- merge(dmeta,
             tmp,
             by = "Sample")

p1 <- ggplot(tmp,
             aes(x = Week,
                 y = TPM,
                 fill = Treatment,
                 group = Treatment)) +
  facet_wrap(~ Geneid,
             scales = "free_y") +
  geom_point(position = position_dodge(0.5),
             shape = 21,
             size = 5,
             color = "black")+
  scale_x_discrete("")
plot(p1)
```

# Session Information
```{r info,eval=TRUE}
sessionInfo()
```